Obstructive Sleep Apnea

By admin On January 19, 2012 Under Mind Power

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How to Diagnose Sleep Disorders : Obstructive Sleep Apnea

SONA FDA-Cleared Anti-Snore and Mild Sleep Apnea Pillow

$49.00

Stop Snoring. Thirty percent of all Americans snore to some degree and up to 50 percent of certain age groups report that they or their sleep partner snore leaving then feeling fatigued and drowsy all day. Between 12 and 20 million Americans suffer from Sleep Apnea, 24 percent are men and 9 percent women. 50 percent with sleep apnea also snore. 1400 die from sleep apnea every year and 38,000 of ca…

Sleep Apnea Pillow – CPAP Pillow – CPAP Nasal Pillow a Sleep Apnea Mask Device Pillow, Pillow For Sleep Apnea

$46.98

Contour Sleep Apnea pillow designed to help patients get a good night’s sleep….

BMV Quantum Subliminal CD Sleep Apnea Aid (Ultrasonic Subliminal Series)

$14.99

Program your subconscious mind for overcoming sleep apnea. Create amazing results using state-of-the-art subliminal and brainwave entrainment technologies. Tune your brainwaves to specific frequencies by listening to this CD! Program your subconscious mind for positive lasting results, created by a Certified Hypnotherapist and NLP Practitioner (Neuro-Linguistic Programming). Silent affirmations, i…

Respironics Premium Chin Strap

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The Respironics Premium Chinstrap features:

Vertical Design that promotes a vertical angle of force on the chin (as opposed to horizontal) in order to reduce the potential of inducing sleep-related events
Integrated Chin Cup that is sewn into the strap to provide a soft and comfortable support without placing unnecessary tension around the chin
Adjustable Support Strap that attaches to a spli…

Ruby Chin Strap – Medium

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The Ruby Chin Strap’s ultra wide bands and continuous flow design provide great stability and fit. Because the Ruby Chin Strap comes in three fixed sizes there is no need for constant adjustment; instead you get a perfect fit all the time.
Part Numbers >> TMS09S-Small, TMS09M-Medium, TMS09L-Large…

Strategies can overcome fear of CPAP mask: parents can help children accept continuous positive airway pressure treatment of obstructive sleep apnea.(Clinical … pressure): An article from: Pediatric News

$5.95

This digital document is an article from Pediatric News, published by Thomson Gale on June 1, 2006. The length of the article is 626 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.Citation DetailsTitle: Strategies can o…

Nursing Care Plans: Nursing Diagnosis and Intervention, 6e (Nursing Care Plans: Nursing Diagnosis & Intervention)

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Nursing Care Plans, 6th Edition is the most comprehensive nursing care planning book on the market, with 183 care plans covering the most common nursing diagnoses and clinical problems in medical-surgical nursing. It reflects the most current clinical practice and professional standards in nursing and presents the content in an easy-to-use, reader-friendly format. The book functions as two books i…

Otolaryngology and Facial Plastic Surgery Board Review: Pearls of Wisdom, Second Edition

$69.95

Why waste time guessing at what you need to know for the otolaryngology board exam? Maximize your exam preparation time with this quick-hit question and answer review. The unique question and single-answer format eliminates the guesswork associated with traditional multiple-choice Q&A reviews and reinforces only the correct answers you’ll need to know on exam day. Emphasis is placed on distilling …

Sleeping Disorder: Find out if you are suffering from a Sleep Disorder and Know What Obstructive Sleep Apnea is and What Sleep Apnea Symptoms are and The Types of Sleep Disorders

$4.97

This book tackles on important issues related to Sleeping Disorders.You will find answers to questions like;Do You Have Sleep Apnea?Could Your Diet Be Keeping You Awake?Does Exercise Affect Your Sleep?Sleep and Your Baby – What’s Normal?Sleep: Is There Such a Thing as Too Much?You will also learn;Signs of Sleep DeprivationSleep and Your HealthTips on Getting Enough Sleep and many moreIf you want t…

Abnormal Respiration: Sleep Apnea, Obstructive Sleep Apnea, Central Neurogenic Hyperventilation, Cough, Snoring, Shortness of Breath

$23.56

Books LLC (Editor),Paperback, English-language edition,Pub by General Books LLC

Ambulatory Anesthesia

$121.45

This issue brings the anesthesiologist up to date on current essential topics in ambulatory anesthesia. Topics covered include obstructive sleep apnea, pediatric ambulatory anesthesia, supraglottic airway devices, issues in office-based ambulatory anesthesia, complex sedation, the role of regional anesthesia in the ambulatory environment, regional catheters, postoperative pain management for the ambulatory patient, and updates on PONV and PDNV. Authors also explore the questions of how much testing should be done, how to make yourself ASC desirable to patients and surgeons, and more.

Ambulatory Anesthesia, An Issue of Anesthesiology Clinics

$105

This issue brings the anesthesiologist up to date on current essential topics in ambulatory anesthesia. Topics covered include obstructive sleep apnea, pediatric ambulatory anesthesia, supraglottic airway devices, issues in office-based ambulatory anesthesia, complex sedation, the role of regional anesthesia in the ambulatory environment, regional catheters, postoperative pain management for the ambulatory patient, and updates on PONV and PDNV. Authors also explore the questions of how much t

Armodafinil

$73.99

High Quality Content by WIKIPEDIA articles! Armodafinil (Nuvigil) is a stimulant-like drug produced by the pharmaceutical company Cephalon Inc., which was approved by the FDA on June 15, 2007. Armodafinil is the active (−)-(R)-enantiomer of the racemic drug modafinil (Provigil). Armodafinil is approved by the FDA for the treatment of narcolepsy and shift work sleep disorder, and as an adjunctive treatment for obstructive sleep apnea.

Assessment of Obstructive Sleep Apnea Syndrome

$77.99

Obstructive Sleep Apnea Syndrome (OSAS) is a very common sleep disorder that is associated with cardiovascular and neurocognitive impairments. The pathophysiological mechanisms underlying the morbidity of OSAS are not completely understood, which make the research on the OSAS an important issue. Obstructive sleep apnea episodes were carefully selected and segmented in three parts, the OSA event and a certain period immediately preceding and following the event, in order to assess the dynamic electroencephalographic (EEG) power changes, in four frequency bands: delta, theta, alpha and beta. Autonomic Nervous System activity was also assessed through the spectral analysis of heart rate variability components in the three mentioned periods. Continuous wavelet transform was the elected spectral analysis technique. To better visualize the EEG spectral changes during OSA episodes across the whole brain, topographic EEG brain mapping was carried out. This research should be especially useful to health professionals, who are focused on sleep disorders, or to engineers interested in the analysis of biomedical signals.

Cerebral blood flow regulation in intermittent hypoxia.

$49.99

Obstructive sleep apnea (OSA) patients are at increased risk of stroke independent of other risk factors; however, this mechanism remains unclear. This increased risk may be related to the OSA patient’s impaired ability to regulate brain blood flow. The purpose of this study was to examine the effects of acute and chronic exposure to intermittent hypoxic apneas (IHA) on dynamic cerebral blood flow regulation in healthy subjects. Each subject performed one 30-s hypoxic apnea every one minute for 20 min on one day (acute protocol) or for 10 days (chronic protocol). During each hypoxic apnea event arterial oxygen saturation reached 80-85%. The rate of regulation (RoR) was calculated as an index of dynamic cerebral autoregulation (CA) from the response of arterial blood pressure and cerebral blood flow velocity to acute hypotension produced by the cuff release technique. The RoR during hypotension was significantly attenuated following the IHA protocol (0.78 +/- 0.09 to 0.47 +/- 0.07 sec; P = 0.003), indicating a loss of dynamic CA as a result of IHA. In addition, RoR was significantly attenuated on days 1 and 10 of the chronic protocol from pre- to post-IHA values (0.78 +/- 0.11 to 0.64 +/- 0.10 sec-1; P = 0.016 and 0.87 +/- 0.15 to 0.46 +/- 0.05 sec-1; P = 0.026). The fluctuations of mean arterial pressure (MAP) and middle cerebral artery blood velocity (MCAV) in response to a single hypoxic apnea were not different before and after intermittent apneas indicating that there was not a loss of cerebral blood flow regulation under a hypertensive stimulus. These findings indicate the increased risk of stroke in the early morning waking hours when the OSA patient faces an orthostatic challenge, such as rising from the supine to the upright position.

Cerebral blood flow regulation in intermittent hypoxia.

$108

Obstructive sleep apnea (OSA) patients are at increased risk of stroke independent of other risk factors; however, this mechanism remains unclear. This increased risk may be related to the OSA patient’s impaired ability to regulate brain blood flow. The purpose of this study was to examine the effects of acute and chronic exposure to intermittent hypoxic apneas (IHA) on dynamic cerebral blood flow regulation in healthy subjects. Each subject performed one 30-s hypoxic apnea every one minute for 20 min on one day (acute protocol) or for 10 days (chronic protocol). During each hypoxic apnea event arterial oxygen saturation reached 80-85%. The rate of regulation (RoR) was calculated as an index of dynamic cerebral autoregulation (CA) from the response of arterial blood pressure and cerebral blood flow velocity to acute hypotension produced by the cuff release technique. The RoR during hypotension was significantly attenuated following the IHA protocol (0.78 +/- 0.09 to 0.47 +/- 0.07 sec; P = 0.003), indicating a loss of dynamic CA as a result of IHA. In addition, RoR was significantly attenuated on days 1 and 10 of the chronic protocol from pre- to post-IHA values (0.78 +/- 0.11 to 0.64 +/- 0.10 sec-1; P = 0.016 and 0.87 +/- 0.15 to 0.46 +/- 0.05 sec-1; P = 0.026). The fluctuations of mean arterial pressure (MAP) and middle cerebral artery blood velocity (MCAV) in response to a single hypoxic apnea were not different before and after intermittent apneas indicating that there was not a loss of cerebral blood flow regulation under a hypertensive stimulus. These findings indicate the increased risk of stroke in the early morning waking hours when the OSA patient faces an orthostatic challenge, such as rising from the supine to the upright position.

Cognitive dysfunction in middle-aged adults vs. older adults with obstructive sleep apnea.

$49.99

Diana C. Dolan,NOOK Study eTextbook, English-language edition,Pub by ProQuest LLC

Dental Management of Sleep Disorders

$104.99

Dental Management of Sleep Disorders is the first text of its kind to focus on the dentist’s role in treating patients with sleep related breathing disorders such as obstructive sleep apnea, sleep bruxism, and snoring.  A practical clinical book, Dental Management of Sleep Disorders highlights the background to these problems, discusses the dentist’s role in their diagnosis and treatment, and outlines clinical strategies and guidance. The book features a full discussi

Evaluating the reliability of risk factors for obstructive sleep apnea in subjects with temporomandibular joint dysfunction.

$49.99

Tammy L. Balatgek,NOOK Study eTextbook, English-language edition,Pub by ProQuest LLC

Evaluation and Management of Obstructive Sleep Apnea, An Issue of Oral and Maxillofacial Surgery Clinics

$73.45

An important review on obstructive sleep apnea for the oral and maxillofacial surgeon! Topics include epidemiology, pathophysiology and clinical features of obstructive sleep apnea; systematic evaluation of the OSA patient; upper airway imaging in the evaluation and surgical management of OSA; management of OSA by continuous positive airway pressure; oral appliances in the treatment of OSA; algorithms for surgical management of obstructive sleep apnea; surgery of the palate, tonsils and tongue; treatment of OSA by distraction osteogenesis; surgical management of OSA in the pediatric patient; anesthetic and postoperative management of the OSA patient, and much more!

Gender differences in baseline functional status and response to continuous positive airway pressure in milder obstructive sleep apnea.

$49.99

Lichuan Ye,NOOK Study eTextbook, English-language edition,Pub by ProQuest LLC

Genetics and Sleep, An Issue of Sleep Medicine Clinics

$101

This issue describes in detail the most current thinking on the way genes affect and determine sleep patterns, behaviors, disorders and needs. Sleep researchers continue to study genetic markers that may someday lead to a personalized approach to treatment of sleep disorders. The genetics of restless legs syndrome, narcolepsy, circadian rhythm disorders, obstructive sleep apnea, parasomnias, and insomnia are discussed. A solid understanding of the role genetics and molecular biology play in sleep will aid clinicians in diagnosing and treating these disorders, as well as advising their patients.

Home Portable Monitoring for Obstructive Sleep Apnea

$101

Home Portable Monitoring for Obstructive Sleep Apnea

Home Portable Monitoring for Obstructive Sleep Apnea, An Issue of Sleep Medicine Clinics

$101

Michael R. Littner,Hardcover,Series: Clinics: Internal Medicine Series, English-language edition,Pub by Elsevier Health Sciences

Just the FACTS101 e-Study Guide for: Evaluation and Management of Obstructive Sleep Apnea, An Issue of Oral and Maxillofacial Surgery Clinics

$5.95

Cram101 Reviews, Scott Boyd,NOOK Book (eBook), Edition: 1, English-language edition,Pub by Cram101

Medifocus Guidebook on: Obstructive Sleep Apnea Syndrome

$18.99

Medifocus,NOOK Book (eBook), English-language edition,Pub by Lulu.com

Medifocus Guidebook on: Obstructive Sleep Apnea Syndrome

$19.5

The MediFocus Guidebook on Obstructive Sleep Apnea Syndrome is the most comprehensive, up-to-date source of information available. You will get answers to your questions, including risk factors of Obstructive Sleep Apnea Syndrome, standard and alternative treatment options, leading doctors, hospitals and medical centers that specialize in Obstructive Sleep Apnea Syndrome, results of the latest clinical trials, support groups and additional resources, and promising new treatments on the horizon. This one of a kind Guidebook offers answers to your critical health questions including the latest treatments, clinical trials, and expert research; high quality, professional level information you can trust and understand culled from the latest peer-reviewed journals; and a unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks. This Guidebook was updated on September 20, 2010.Obstructive sleep apnea syndrome may be defined as a cessation of breathing characterized by repetitive episodes of airway obstruction caused by collapse of the upper airway during sleep. Classic features of patients with obstructive sleep apnea syndrome include: * Excessive daytime sleepiness * Loud snoring during sleep * Fatigue * Obesity or being overweightResearch has suggested that there is a strong association between obstructive sleep apnea syndrome and cardiovascular diseases including: * Hypertension – high blood pressure * Congestive heart failure – accumulation of fluids in the lungs and other body tissues caused by insufficient pumping of blood by the heart muscles * Arrhythmias – irregular heart beats * Stroke * Angina pectoris – chest pain that occurs in people with underlying coronary artery diseasePolysomnography (overnight sleep test) is considered to be the most accurate test available for establishing

Medifocus Guidebook on: Obstructive Sleep Apnea Syndrome

$19.95

Medifocus.com, Elliot Jacob (Editor),Paperback, English-language edition,Pub by CreateSpace

Modafinil

$51

Modafinil is an analeptic drug manufactured by Cephalon, and is approved by the U.S. Food and Drug Administration (FDA) for the treatment of narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea. Modafinil, like other stimulants, increases the release of monoamines, specifically the catecholamines norepinephrine and dopamine, from the synaptic terminals. However, modafinil also elevates hypothalamic histamine levels, leading some researchers to consider Modafinil a “wakefulness promoting agent” rather than a classic amphetamine-like stimulant (as evidenced by the difference in c-Fos distribution caused by modafinil as compared to amphetamine). Despite modafinil’s histaminergic action, it still partially shares the actions of amphetamine-class stimulants due to its effects on norepinephrine and dopamine. An NIAAA study highlighted “the need for heightened awareness for potential abuse of and dependence on modafinil in vulnerable populations” due to the drug’s effect on dopamine in the brain’s reward center.

Obesity Hypoventilation Syndrome

$62.33

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. High Quality Content by WIKIPEDIA articles! Obesity hypoventilation syndrome (also known as Pickwickian syndrome) is a condition in which severely overweight people fail to breathe rapidly enough or deeply enough, resulting in low blood oxygen levels and high blood carbon dioxide (CO2) levels. Many people with this condition also frequently stop breathing altogether for short periods of time during sleep (obstructive sleep apnea), resulting in many partial awakenings during the night, which leads to continual sleepiness during the day. The disease puts strain on the heart, which eventually may lead to the symptoms of heart failure, such as leg swelling and various other related symptoms. The most effective treatment is weight loss, but it is often possible to relieve the symptoms by nocturnal ventilation with positive airway pressure (CPAP) or related methods.

Obesity and Respiratory Disease, An Issue of Clinics in Chest Medicine

$12.16

Topics include: The Obesity Epidemic, Altered Resting and Exercise Respiratory Physiology in Obesity, Association of Asthma and Other Obstructive Lung Diseases and Obesity, Role of Obesity in Obstructive Sleep Apnea, The Pickwickian Syndrome – Obesity Hypoventilation Syndrome, Obesity and Thromboembolic Disease, Medical Therapy of Obesity, Obesity and Bariatric Surgery, Airway Management of Patients with Obesity, Anesthetic Management of Patients with Obesity, Obesity and Acute Lung Injury, Obese Patients in the Intensive Care Units, Obesity Cardiomyopathy, Obesity and Respiratory Diseases in Childhood, Obesity and Respiratory Diseases in the Aging Population.

Obstructive Sleep Apnea

$50.42

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. High Quality Content by WIKIPEDIA articles! Obstructive sleep apnea (OSA) is a common sleep apnea caused by obstruction of the airway. It is characterized by pauses in breathing during sleep. These episodes, called apneas (literally, “without breath”), each last long enough that one or more breaths are missed, and occur repeatedly throughout sleep. In obstructive sleep apnea, breathing is interrupted by a physical block to airflow, despite the effort to breathe.

Obstructive Sleep Apnea

$25

Barbara Phillips, Matthew T. Naughton,Paperback, Edition: 1,Series: Fast Facts (Health Press) Ser., English-language edition,Pub by Health Press UK

Obstructive Sleep Apnea – A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

$28.95

This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to obstructive sleep apnea. It also gives extensive lists of bibliographic citations. Finally, it provides information to users on how to update their knowledge using various Internet resources. The book is designed for physicians, medical students preparing for Board examinations, medical researchers, and patients who want to become familiar with research dedicated to obstructive sleep apnea.If your time is valuable, this book is for you. First, you will not waste time searching the Internet while missing a lot of relevant information. Second, the book also saves you time indexing and defining entries. Finally, you will not waste time and money printing hundreds of web pages.

Obstructive Sleep Apnea – a Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

$32.27

In March 2001, the National Institutes of Health issued the following warning: “The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading.” Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing. Since only the smallest fraction of information dealing with obstructive sleep apnea is indexed in search engines, such as www.google.com or others, a non-systematic approach to Internet research can be not only time consuming, but also incomplete. This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so.

Obstructive Sleep Apnea And Cognition In Children.

$102

Maria Elizabeth Barnes,Paperback, English-language edition,Pub by ProQuest, UMI Dissertation Publishing

Obstructive Sleep Apnea And Pre-Eclampsia

$69

Fairouz Sabah Saad,Paperback, English-language edition,Pub by ProQuest, UMI Dissertation Publishing

Obstructive Sleep Apnea In Adults

$196

Obstructive Sleep Apnea In Adults

Obstructive Sleep Apnea Syndrome And Epilepsy

$62.39

Baharudin Abdullah, Muhammad Yusri Musa, John Tharakant,Paperback, English-language edition,Pub by VDM Verlag

Obstructive Sleep Apnea in Adults: Relationship with Cardiovascular and Metabolic Disorders

$176.39

A. Lurie (Editor), Contribution by J. S. Borer,Hardcover,Series: Advances in Cardiology Series, English-language edition,Pub by Karger, S. Inc.

Obstructive Sleep Apnea: Diagnosis and Treatment

$240

Clete A. Kushida (Editor),Hardcover,Series: Sleep Disorders, English-language edition,Pub by Informa Healthcare

Obstructive Sleep Apnea: Memory and mammillary bodies.

$49.99

Matt S. Gee,NOOK Study eTextbook, English-language edition,Pub by ProQuest LLC

Obstructive Sleep Apnea: Pathophysiology, Comorbidities, and Consequences

$240

Responding to the growing recognition of Obstructive Sleep Apnea (OSA) as a major medical condition and the emergence of exciting new therapies, this source analyzes the clinical features, characteristics, comorbidities, and impact of OSA on patient biological systems and quality-of-life. Edited by the Director of the Center for Human Sleep Research at Stanford, this source supplies an all-encompassing guide to the comorbid medical conditions and socioeconomic impact of OSA.

Obstructive sleep apnea and cognition in children.

$49.99

In an estimated 1-3% of children, Obstructive Sleep Apnea (OSA) is likely responsible for behavioral and neurocognitive dysfunction. Recently, the American Academy of Pediatrics highlighted the need to study the progression of pediatric OSA after surgical intervention. In previous studies, measures of neurocognitive function were based on questionnaires completed by the caregiver. A more objective and reliable measure of the efficacy of adenotonsillectomy (AT) for OSA is needed. The candidate proposed two aims: (1) measuring cognitive and electrophysiological changes in children with OSA before and after AT using event-related potentials (ERP); (2) examining the postoperative changes in clinical symptoms with behavioral tasks, standard neuropsychological assessments, and physiological measures, such as polysomnography (PSG). Forty-eight enrollees (20 with OSA and 28 controls) took part in 2 ERP tasks—Oddball and Directional Stroop—and a neurocognitive battery including the NEPSY and Child Behavior Checklist (CBCL) at the initial test session. These were repeated at the 6-month follow-up session. ERP data were analyzed using traditional amplitude and latency measurements; temporal principal components analysis (PCA); and source localization and dipole analysis. These analyses provided dependent variables for the subsequent repeated measures ANOVA and multiple regression analyses. The time-locked waveforms were used to form spatial models that localized electrical activity in the brain. Finally, ERP differences between children with OSA and controls were related to neurocognitive outcomes. The candidate hypothesized that children diagnosed with OSA by overnight PSG would exhibit differences in ERPs when presented with auditory and visual tasks that tap the cognitive functions of the brain’s frontal lobes and that these differences would normalize after surgical treatment. These hypotheses were confirmed. Children with suspected OSA had significantly altered

Obstructive sleep apnea and pre-eclampsia: Is there an association?

$49.99

Pre-eclampsia is a life threatening disease that is specific for pregnancy. It affects 9% of pregnant population and it has negative implications on the health of the mother and the fetus. It is characterized by high Blood Pressure (equal or above to 140/80mmHg), increased protein in the urine (equal or above .03g/24 hour collection), and general edema. Obstructive sleep apnea (OSA) is a sleep breathing disorder characterized by recurrent episodes of breathing cessation accompanied by oxygen desaturation and/or arousal. It occurs in 4% in women and 9% in men and is under diagnosed especially among women. Both pre-eclampsia and OSA share a significant overlap in risk factors especially hypertension, metabolic syndrome, and cardiovascular diseases in general. The objective of this study is to examine the association between pre-eclampsia and OSA and the specific aim is to test the hypothesis that the pre-eclamptic women are at higher risk of OSA than women with normal uncomplicated pregnancies. It is a clinic-based case control study. Cases were all pre-eclamptic patients admitted to University of Louisville (UofL) hospital or attending the high risk maternity clinic between August20–November30, 2007. Controls were healthy pregnant women attending UofL continuity clinic during the same period. Patients were asked to complete three questionnaires: the Berlin questionnaire, the Epworth Sleepiness Scale, and the Fatigue Severity Scale. Demographic data was also collected. Distributions of study subjects with respect to the different variables were calculated. Odds ratios and 95% confidence intervals were also calculated for risk of OSA, excessive daytime sleepiness, and fatigue. The results show that pre-eclamptic women are at higher risk of having OSA, excessive daytime sleepiness, and fatigue than healthy pregnant women. Most demographic characteristics like age, race, height, BMI, weight gain, family history of OSA, previous history of OSA, smoking, and alcohol

Otolaryngology Cases: The University of Cincinnati Clinical Portfolio

$89.99

Designed to prepare otolaryngology residents and practitioners for the sort of cases they will see in daily practice, this comprehensive review provides readers with systematic, up-to-date coverage of every major ENT specialty, including otology and neurotology, the skull base, rhinology, laryngology, head and neck cancer, sleep disorders, pediatric otolaryngology, trauma, facial plastic and reconstructive surgery, and more.Each carefully selected case follows a consistent user-friendly format that guides the user through history, differential diagnosis, test interpretation, the definitive diagnosis, medical and surgical management, rehabilitation, and follow-up. The authors provide clearly articulated management algorithms and contemporary assessment strategies for each clinical scenario. Multiple-choice questions appear at the end of each chapter to enhance understanding of the case studies and optimize the learning experience.Features:- 88 clinical cases direct from the experts at the University of Cincinnati, Department of Otolaryngology-Head and Neck Surgery- Discussion of key ENT topics, such as otitis media, sudden sensorineural hearing loss, spasmodic dysphonia, the facial nerve, obstructive sleep apnea, and more- More than 150 illustrations, including full-color intraoperative images and high-quality radiographs- Consistent presentation throughout the book enhances ease-of-use- 282 multiple-choice review questions that are ideal for self-assessment- Extensive bibliography with references to the current literaturePractical and concise, this must-have book is an indispensable tool for ENT residents and fellows. It also serves as a handy refresher for experienced physicians in otolaryngology-head and neck surgery, primary care, pediatrics, and internal medicine who are looking for an efficient way to hone their diagnostic and management skills.

Outlines & Highlights for Evaluation and Management of Obstructive Sleep Apnea, An Issue of Oral and Maxillofacial Surgery Clinics by Scott B. Boyd

$44.1

Cram101 Textbook Cram101 Textbook Reviews,Paperback, English-language edition,Pub by Academic Internet Publishers

Parasomnias

$10.75

Purchase includes free access to book updates online and a free trial membership in the publisher’s book club where you can select from more than a million books without charge. Chapters: Sleepwalking, Homicidal Somnambulism, Sleep Sex, Parasomnia, Night Terror, Night Eating Syndrome, Catathrenia, Somniloquy, Sleep Emailing. Excerpt: Catathrenia , a rapid eye movement sleep parasomnia consisting of breath holding and expiratory groaning during sleep , is distinct from both somniloquy and obstructive sleep apnea . The sound is produced during exhalation as opposed to snoring which occurs during inhalation. It is usually not noticed by the person producing the sound but can be extremely disturbing to sleep partners, although once aware of it, sufferers tend to be woken up by their own groaning as well. Bed partners generally report hearing the person take a deep breath, hold it, then slowly exhale; often with a high-pitched squeak or groaning sound. Catathrenia typically occurs during REM sleep , although it may also occur to a lesser degree during NREM sleep. Often the groaning occurs toward the end of the sleep cycle, within a couple hours of waking. In many cases it occurs exclusively during REM sleep. Catathrenia begins with a deep inspiration. The sufferer will the holds one’s breath against a closed glottis , similar to the valsalva maneuver . After a period of time and some blood oxygen desaturation, there is an arousal, followed by expiration. Expiration can be slow and accompanied by sound caused by vibration of the vocal cords or a simple rapid exhalation with no sound. There is a debate whether the cause is physical or neurological, a question that requires further study. While some speculate about a direct correlation to high stress or the concept that this purely psychological, there is only anecdotal evidence of either cause. Catathrenia has been defined as a parasomnia in the International Classification of Sleep Disorders Diagnostic and

Principles And Practice Of Pediatric Sleep Medicine

$98.95

This companion to Kryger et al.’s PRINCIPLES AND PRACTICE OF SLEEP MEDICINE focuses on the diagnosis and treatment of a full range of sleep disorders in children. Recognized leaders in the field offer definitive guidance on virtually all of the sleep-associated problems encountered in pediatrics, from sleep and colic…to obstructive sleep apnea, neurological disorders, and hypersomnias…to sleep-related enuresis.

Principles and Practice of Pediatric Sleep Medicine

$98.95

This companion to Kryger et al.’s PRINCIPLES AND PRACTICE OF SLEEP MEDICINE focuses on the diagnosis and treatment of a full range of sleep disorders in children. Recognized leaders in the field offer definitive guidance on virtually all of the sleep-associated problems encountered in pediatrics, from sleep and colic…to obstructive sleep apnea, neurological disorders, and hypersomnias…to sleep-related enuresis.• Presents up-to-date information of the field’s hottest topics in chap

Pulsus Paradoxus

$59

Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. High Quality Content by WIKIPEDIA articles! In medicine, a pulsus paradoxus (PP), also paradoxic pulse and paradoxical pulse, is an exaggeration of the normal variation in the pulse during the inspiratory phase of respiration, in which the pulse becomes weaker as one inhales and stronger as one exhales. It is a sign that is indicative of several conditions including cardiac tamponade, pericarditis, chronic sleep apnea, croup, and obstructive lung disease (e.g. asthma, COPD). The paradox in pulsus paradoxus is that, on clinical examination, one can detect beats on cardiac auscultation during inspiration that cannot be palpated at the radial pulse.

Reflux Disease: Causes, Symptoms and Treatment

$78.99

Gastroesophageal reflux disease (GERD), or acid reflux disease is defined as chronic symptoms or mucosal damage produced by the abnormal reflux in the esophagus. This is commonly due to transient or permanent changes in the barrier between the esophagus and the stomach. This new book focuses on varied topics relating to reflux disease including: the role of mucosal inflammation in reflux disease, pharmacologic treatment of GERD, pediatric gastroesophageal reflux disease, paraesophageal hernias and laparoscopic antireflux procedures, minimally invasive treatments of gastroesophageal reflux disease, obstructive sleep apnea and GERD, and others.

Relationship of obstructive sleep apnea and sickle cell disease severity in children.

$49.99

Statement of the Problem. Obstructive sleep apnea (OSA) initiates hypoxemia and elevated inflammatory markers, events which contribute to vaso-occlusion in sickle cell disease (SCD) independent of OSA. Children with SCD are at increased risk of developing OSA due to SCD-related adenotonsillar hypertrophy, and OSA may increase vaso-occlusion and SCD severity through hypoxemia and inflammation. Identification of OSA-related factors influencing SCD severity is important to reduce SCD-related complications.;Purpose. The purpose of this study was to test the hypotheses that SCD severity is associated with OSA, is associated with OSA-related changes in polysomnography parameters and treatment of OSA with adenotonsillectomy decreases SCD severity. Methods: A case series study was conducted collecting data from the medical record. Subjects were children aged 2-18 years with SCD, referred to a sleep laboratory for evaluation of OSA. Outcome measures included rates of help-seeking behaviors (medical contacts and days of care) for vaso-occlusive crises at 2 time points, and a Sickle Cell Disease Severity Index (DSI) score. Analyses were descriptive and nonparametric, with exploratory regression modeling.;Results. Younger children had more severe OSA ( r=-.314, p=.017), and older children had more severe SCD (medical contacts, r=.303, p=.021; days of care, r=.369, p=.007). Underweight adolescents had the highest obstructive apnea-hypopnea indexes (OAHI). Medical contacts decreased as OSA severity increased, H(2)=7.85, p<.05; and days of care showed a decreasing trend with increasing OSA severity, r=-.26, p<.01. Medical contacts were negatively associated with OAHI (p<.01), respiratory arousal index (p<.01) and peak end-tidal CO 2 (p<.05); days of care were negatively associated with OAHI (p<.05); and DSI scores were negatively associated with mean sleep oxyhemoglobin saturation (p<.01) and sleep efficiency (p<.05). Children with OSA having

Relationship of obstructive sleep apnea and sickle cell disease severity in children.

$108

Statement of the Problem. Obstructive sleep apnea (OSA) initiates hypoxemia and elevated inflammatory markers, events which contribute to vaso-occlusion in sickle cell disease (SCD) independent of OSA. Children with SCD are at increased risk of developing OSA due to SCD-related adenotonsillar hypertrophy, and OSA may increase vaso-occlusion and SCD severity through hypoxemia and inflammation. Identification of OSA-related factors influencing SCD severity is important to reduce SCD-related complications.;Purpose. The purpose of this study was to test the hypotheses that SCD severity is associated with OSA, is associated with OSA-related changes in polysomnography parameters and treatment of OSA with adenotonsillectomy decreases SCD severity. Methods: A case series study was conducted collecting data from the medical record. Subjects were children aged 2-18 years with SCD, referred to a sleep laboratory for evaluation of OSA. Outcome measures included rates of help-seeking behaviors (medical contacts and days of care) for vaso-occlusive crises at 2 time points, and a Sickle Cell Disease Severity Index (DSI) score. Analyses were descriptive and nonparametric, with exploratory regression modeling.;Results. Younger children had more severe OSA ( r=-.314, p=.017), and older children had more severe SCD (medical contacts, r=.303, p=.021; days of care, r=.369, p=.007). Underweight adolescents had the highest obstructive apnea-hypopnea indexes (OAHI). Medical contacts decreased as OSA severity increased, H(2)=7.85, p<.05; and days of care showed a decreasing trend with increasing OSA severity, r=-.26, p<.01. Medical contacts were negatively associated with OAHI (p<.01), respiratory arousal index (p<.01) and peak end-tidal CO 2 (p<.05); days of care were negatively associated with OAHI (p<.05); and DSI scores were negatively associated with mean sleep oxyhemoglobin saturation (p<.01) and sleep efficiency (p<.05). Children with OSA having

Secondary Hypertension

$2

Our knowledge of secondary hypertension has grown significantly in recent years with the introduction of new diagnostic tools, biochemical tests, and drugs. In Secondary Hypertension: Clinical Presentation, Diagnosis, and Treatment, world-renowned researchers and clinicians critically evaluate and summarize the latest ideas about the screening, diagnosis, and medical/surgical treatment of secondary hypertension in adults and children. Drawing on a variety of medical disciplines-including nephrology, endocrinology, internal medicine, and pediatrics-the book’s authors review the critical scenarios that should prompt a search for secondary forms of hypertension and discuss appropriate testing for these uncommon disorders. Additional coverage is given to exogenous or such less-appreciated causes of secondary hypertension as obstructive sleep apnea, primary aldosteronism, renovascular hypertension, and the effects of noncardiac drugs.Comprehensive and up-to-date, Secondary Hypertension: Clinical Presentation, Diagnosis, and Treatment is an indispensable guide for physicians seeking the special knowledge and expertise needed to diagnose and treat the many varieties of secondary hypertension in adults and children.

Secondary Hypertension

$104

This indispensable guide critically evaluates for hypertension specialists both established and new techniques for diagnosing and treating secondary hypertension in adults and children. Drawing on a variety of medical disciplines-including nephrology, endocrinology, internal medicine, and pediatrics-its world-renowned authors review the critical scenarios that should prompt a search for secondary forms of hypertension, and detail appropriate testing for these uncommon disorders. Additional coverage is given to exogenous or such less-appreciated causes of secondary hypertension as obstructive sleep apnea, primary aldosteronism, renovascular hypertension, and the effects of noncardiac drugs.

Sleep

$121.45

This issue offers a valuable update in the fast-moving specialty of sleep medicine. Topics covered include: The Neurobiology of Sleep; Adult Obstructive Sleep Apnea; Central Sleep Apnea (including complex sleep apnea and ASV); Pediatric Sleep-Related Breathing Disorders; Hypoventilation Syndromes; Metabolism in OSA; Cardiovascular Consequences of Sleep Apnea; Home Sleep Apnea Testing; Insomnia; Excessive Sleepiness; Narcolepsy; Restless Leg Syndrome and Movement Disorders; Parasomnia; Circadian Rhythm Sleep Disorders; Medication Effects on Sleep; and Polysomnography.

Sleep Apnea Syndrome in the Stomatognathic System

$48.99

Obstructive sleep apnea is a disorder characterized by repetitive, complete or partial closure of the upper airway during sleep. Many factors, including craniofacial abnormalities, influence upper airway obstruction during sleep. Sleep apnea syndrome (SAS) is related to different combinations of anatomical and functional aspects that produce the airway collapse in individual patients. To compensate for the craniofacial abnormalities and treat sleep apnea, there are some dental and maxillofacial surgical modalities. In this book, treatment and research of SAS are described mainly from clinical and neurophysiological aspects in the stomatognathic system.

Sleep Apnea: What is Sleep Apnea? Sleep Apnea Symptoms, Causes of Sleep Apnea, Taking a Sleep Apnea Test, Dangers of Obstructive Sleep Apnea, Sleep Apnea in Children, and Sleep Apnea Treatments

$7.97

Debra Thomason,NOOK Book (eBook), English-language edition,Pub by Lamont Hall Publishing

Sleep Disorders

$94.5

Authoritative clinicians present up-to-date, concise, and practical advice on the diagnosis and treatment of the most common sleep disorders encountered in general practice. They not only review such problems as obstructive sleep apnea, insomnia, circadian rhythm disorders, and narcolepsy, but they also discuss such important topics as pediatric sleep disorders, the pharmacology of sleep medicines, diagnostic testing and technology, and the use of bright light therapy in sleep disorders and depression. Throughout, the emphasis is on obtaining an appropriate patient history and carefully analyzing the available diagnostic and treatment strategies to determine appropriate therapeutic regimens.

Sleep Disorders in Women: A Guide to Practical Management

$2.86

This multidisciplinary review of all aspects of sleep disorders in women at different stages of life emphasizes the unique impact that each reproductive and endocrine stage has on both normal sleep and sleep disorders. The authors share their expert knowledge and experience in treating insomnia, excessive daytime sleepiness, restless leg syndrome, and obstructive sleep apnea in adolescent, premenopausal, pregnant, and menopausal patients. In addition to summarizing the latest, cutting-edge research in a succinct and clinically relevant manner, the authors also help physicians recognize the symptom patterns of sleep disorders in their female patients and offer guidance on diagnosing and treating them in a timely fashion.

Sleep Disorders in Women: From Menarche Through Pregnancy to Menopause: A Guide for Practical Management

$99.53

It is now well recognized that many health disorders are either unique to or more common among women than men. In Sleep Disorders in Women: A Guide to Practical Management, a multidisciplinary panel of eminent researchers and practicing clinicians comprehensively explores all aspects of sleep disorders in women at different stages of life, illuminating the unique impact that each reproductive and endocrine stage has on both normal sleep and sleep disorders. The authors-gynecologists, neurologists, pulmonologists, pediatricians, psychiatrists, physician assistants, and psychologists-share their expert knowledge and experience in treating insomnia, excessive daytime sleepiness, restless legs syndrome, and obstructive sleep apnea in adolescent, premenopausal, pregnant, and menopausal patients. Less commonly appreciated circadian rhythm disorders in adolescents such as delayed sleep phase syndrome and insomnia are also addressed. In addition to summarizing the latest, cutting-edge research in a succinct and clinically relevant manner, the authors also help physicians recognize the symptom patterns of sleep disorders in their female patients and offer guidance on diagnosing and treating them in a timely fashion. Introductory chapters provide essential background information on the epidemiology of sleep disorders in women, how to workup female patients with sleep complaints, and the impact of the life cycle on sleep in women. Authoritative and clinically oriented, Sleep Disorders in Women: A Guide to Practical Management clarifies for today’s busy clinicians the complexities of sleep physiology and sleep pathophysiology in women, so that they can more easily make accurate diagnoses and offer optimal treatments.

Sleep Disorders in Women: From Menarche Through Pregnancy to Menopause: A Guide for Practical Management

$1.99

It is now well recognized that many health disorders are either unique to or more common among women than men. In Sleep Disorders in Women: A Guide to Practical Management, a multidisciplinary panel of eminent researchers and practicing clinicians comprehensively explores all aspects of sleep disorders in women at different stages of life, illuminating the unique impact that each reproductive and endocrine stage has on both normal sleep and sleep disorders. The authors-gynecologists, neurologists, pulmonologists, pediatricians, psychiatrists, physician assistants, and psychologists-share their expert knowledge and experience in treating insomnia, excessive daytime sleepiness, restless legs syndrome, and obstructive sleep apnea in adolescent, premenopausal, pregnant, and menopausal patients. Less commonly appreciated circadian rhythm disorders in adolescents such as delayed sleep phase syndrome and insomnia are also addressed. In addition to summarizing the latest, cutting-edge research in a succinct and clinically relevant manner, the authors also help physicians recognize the symptom patterns of sleep disorders in their female patients and offer guidance on diagnosing and treating them in a timely fashion. Introductory chapters provide essential background information on the epidemiology of sleep disorders in women, how to workup female patients with sleep complaints, and the impact of the life cycle on sleep in women. Authoritative and clinically oriented, Sleep Disorders in Women: A Guide to Practical Management clarifies for today’s busy clinicians the complexities of sleep physiology and sleep pathophysiology in women, so that they can more easily make accurate diagnoses and offer optimal treatments.

Sleep Disorders: Diagnosis and Treatment

$94.5

The dramatic increase in the prevalence of individual sleep disturbances, as well as in our knowledge of their mechanisms, has made urgent the need for a new and up-to-date physician’s guide. With contributions from leading clinicians, Poceta’sand Mitler’s Sleep Disorders satisfies this need by bringing together clear, concise, and practical advice on the diagnosis and treatment of the most common sleep disorders encountered in general practice. Not only do these highly experienced writers review such problems as obstructive sleep apnea, insomnia, circadian rhythm disorders, and narcolepsy, but also such important topics as pediatric sleep disorders, the pharmacology of sleep medicines, diagnostic testing and technology, and the use of bright light therapy in sleep disorders and depression. Throughout, the emphasis is on obtaining an accurate history from a patient with a sleep complaint, on carefully analyzing the available diagnostic techniques, and finally devising appropriate treatment strategies and their therapeutic regimens. Sleep Disorders is written for clinicians, by clinicians. Its authoritative, up-to-date treatment, practical approach, and easy accessibility will make it the gold-standard guide for all primary care physicians desiring to better diagnose and treat their patients’ sleep disorders.

Sleep Medicine, an Issue of Primary Care: Clinics in Office Practice

$157.03

This edition provides primary care physicians a thorough review of sleep medicine. Articles include: overview of sleep; obstructive sleep apnea; central sleep apnea; insomnia; narcolepsy and disorders of excessive somnolence; parasomnias; restless legs syndrome and periodic limb movement disorder; circadian sleep disorders; sleep deprivation; medications; sleep in patients with medical disorders and neurologic and psychiatric disorders; pediatric sleep disorders; sleep among women; and sleep in the elderly.

Sleep Physiology: Sleep and Learning, Sleep Apnea, Nocturnal Emission, Rapid Eye Movement Sleep, Obstructive Sleep Apnea

$24.54

Sleep Physiology: Sleep and Learning, Sleep Apnea, Nocturnal Emission, Rapid Eye Movement Sleep, Obstructive Sleep Apnea

Sleep physiology: Sleep and learning, Sleep apnea, Nocturnal emission, Rapid eye movement sleep, Obstructive sleep apnea

$31.4

Source: Source: Wikipedia,Paperback, English-language edition,Pub by General Books LLC

Sleep, An Issue of Clinics in Chest Medicine

$99.75

This issue offers a valuable update in the fast-moving specialty of sleep medicine. Topics covered include: The Neurobiology of Sleep; Adult Obstructive Sleep Apnea; Central Sleep Apnea (including complex sleep apnea and ASV); Pediatric Sleep-Related Breathing Disorders; Hypoventilation Syndromes; Metabolism in OSA; Cardiovascular Consequences of Sleep Apnea; Home Sleep Apnea Testing; Insomnia; Excessive Sleepiness; Narcolepsy; Restless Leg Syndrome and Movement Disorders; Parasomnia; Circadian Rhythm Sleep Disorders; Medication Effects on Sleep; and Polysomnography.

Sleep, An Issue of Medical Clinics

$25

This issue of Medical Clinics of North America is guest edited by Dr. Christian Guilleminault, one of the world’s leading experts in the field of sleep medicine. He is attributor of the Christian Guilleminault Award for Research in Sleep Medicine bestowed by the World Association of Sleep Medicine. He has put together an outstanding issue that provides the most essential information for the internist on diagnosis and treatment. Topics such as insomnia, excessive sleepiness, REM behavior disorder, restless legs syndrome, obstructive sleep apnea, narcolepsy, pediatric sleep disorders, cognitive behavior therapy, pharmacologic therapy, sleep as it relates to various major medical disorders, and more.

Snore No More

$9.13

Snore No More provides value information on how to help yourself; family members, friends, or roommates stop snoring and live longer, healthier and happier.This fourth edition of Snore No More outlines easy-to-understand facts about the causes of snoring and the dangers of loud snoring. It prescribes preventatives measures, self-help methods, where to get professional help, and the state-of-the-art cutting edge treatments available to stop snoring and obstructive sleep apnea (OSA). This edition introduces Oral Systemic Balance® Therapeutic Systems, a new therapeutic approach to treating snoring, sleep apnea and a wide variety of other symptoms including TemporoMandibular Joint (TMJ); and many other pain conditions and agitation states.Snore No More features some intriguing real-life accounts given by sleep apnea patients that describe physical and mental suffering, loss of job, sexual and marital problems and near-death situations caused by loud snoring and OSA. The author shares his 39 year battle with his own “obnoxious” heavy snoring and OSA.

Snoring and Obstructive Sleep Apnea

$2.11

David N. F. Fairbanks, Shiro Fujita (Editor),Hardcover – REV, Edition: 2, English-language edition,Pub by Lippincott Williams & Wilkins

Snoring and Obstructive Sleep Apnea

$98.9

Completely updated, this volume is a practical, authoritative guide to the diagnosis and management of sleep-related breathing disorders. This Third Edition provides a more comprehensive treatment approach, focusing on surgical treatment but recognizing the growing importance of medical management of snoring/sleep disorders. Noted experts in the fields of otolaryngology, head and neck surgery, pulmonology, and sleep medicine examine the pathophysiology of these disorders, their clinical presentations in adults and children, the diagnostic workup, and the latest and most effective drugs, devices, oral appliances, and surgical procedures. An in-depth discussion of patient selection and treatment decisions is also included.

Snoring and Obstructive Sleep Apnea

$141.02

Snoring and Obstructive Sleep Apnea

Snoring and Obstructive Sleep Apnea Syndrome

$79.51

Snoring and Obstructive Sleep Apnea Syndrome

Surgery for Snoring and Obstructive Sleep Apnea Syndrome

$416

Mario Fabiani (Editor),Library Binding, English-language edition,Pub by Kugler Publications

The Encyclopedia of Sleep and Sleep Disorders

$75

The Encyclopedia of Sleep and Sleep Disorders, Third Edition examines the key terms, conditions, remedies, long-term health consequences, and advances that have been made in sleep health, sleep research, and sleep disorder diagnosis and treatment. This timely revised edition covers more than 80 sleep disorders in more than 800 entries and includes three informative essays History of Sleep and Man, Psychology of Sleep, and Sociology of Sleep, the latter of which is new to this edition. An all-new introduction, helpful appendixes, a bibliography, and an index complete this extensive encyclopedia. Topics include: -Accidents -Biological clock -Diet and sleep -Elderly and sleep -Infant sleep -Melatonin -Narcolepsy -Obstructive sleep apnea syndrome -Restless leg syndrome -Surgery and sleep disorders -and more.

The Neuropsychology Of Breathing-Related Sleep Disorders

$66.99

Obstructive sleep apnea (OSA) is a complex disorder of neural respiratory control and upper airway dysfunction that results in repeated complete and partial occlusion of the upper airway during sleep. Obstructive sleep apnoea has been linked to fatigue, increased rates of road and work-related accidents and deficits across a range of neurocognitive domains. The most widely used treatment for OSA is continuous positive airway pressure (CPAP). The author investigates the effects of OSA on neurocognitive functioning, simulated driving performance, vigilance, and objective and subjective sleepiness, and answers the question: is treatment with CPAP effective in alleviating any or all of these deficits? These issues are discussed in light of the importance of detecting such impairments in order to minimise the risk of accidental injury to sufferers of OSA and others. This book will be of interest to psychologists, sleep researchers, and scientists in general.

The relationship among chronic pain, opiates, and sleep.

$49.99

Purposes. The overall aim of this study was to examine the relationships among chronic pain, opiates, respiration, and sleep in a sample of subjects referred for assessment of sleep disorders. This study assessed: (a) whether increasing dosages of opiate predict severity of sleep disordered breathing, sleep architecture, sleep continuity abnormalities, and/or excessive daytime sleepiness; (b) whether the study groups ([no pain vs. pain] and [pain minus opiate treatment vs. pain plus opiate treatmentl) differed with respect to severity of sleep disordered breathing, sleep architecture, sleep continuity abnormalities; (c) whether the known risk factors for sleep disordered breathing differed for persons with and without chronic pain, and (d) whether intensity of pain predicted severity of sleep disordered breathing.;Methods. A descriptive cross sectional study was conducted. There were two types of independent variables, (a) risk factors for sleep disordered breathing (BMI, age, gender, number of systems affected by co-morbid diseases, and presence of anatomical abnormalities typical of obstructive sleep apnea), and (b) those that were directly related to the investigational hypothesis (pain incidence and intensity and/or opiate use and dose). Dependent Variables included: measures of sleep disordered breathing (e.g., frequency of central and obstructive events), sleep architecture (e.g., percent of stages 1-4 and REM), and sleep continuity measures (e.g., Sleep Latency, Number of Awakenings, and Total Sleep Time). After orthogonally coding for group membership, regression models were used for statistical analysis.;Results. Data was collected on a total of 419 subjects (no pain [n = 171], pain –opiate Tx [n = 187], and pain +opiate Tx [n = 61]). Sample demographic (mean +/- SD) was as follows: age 50 yr +/- 12.; 51% male; BMI 33.8 +/- 7; Epworth Sleepiness Scale 10.3 +/- 5; pain intensity 3.8 +/- 2 (0-10 scale); morphine equivalent dose 152 +/- 195 mg; and 98% of

The role of protein kinase A in hypoxia-induced PC-12 cell death.

$49.99

Hypoxia is characterized by an inadequate oxygen supply to the tissues in proportion to their metabolic needs, and is a primary factor in traumatic CNS injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The cAMP-dependent protein kinase (PKA) has been attributed a role as an anti-apoptotic kinase as well as a pro-apoptotic signal. Thus the role of PKA in hypoxia-induced cell survival is currently unclear. We show here that hypoxia induces cell death in WT PC-12 cells, pheochromocytoma cells used as a model of the oxygen-sensitive carotid body glomus cells. The onset of cell death following 24 hours of severe, sustained hypoxia also correlated with an increase in oxidative stress and a drop in ATP levels. Inactivation of PKA in the 123.7 PC-12 cell line prevented the hypoxia-induced ROS surge, energy depletion, and cell death. PKA activity thus contributes to hypoxia-induced cell death in WT cells via enhanced ROS production and energy depletion, but was not shown to play a role in the regulation of cellular antioxidant mechanisms. 123.7 cells had lower levels of hypoxia-induced glucose utilization and lactate release than WT cells, thus PKA appears to stimulate increases in glycolytic flux during hypoxia. Mitochondrial potentials were higher in 123.7 cells than in WT cells, indicating that PKA inhibits mitochondrial metabolism. Furthermore, the expression of COX IV was decreased by hypoxic exposure in both cell types, but was significantly greater in 123.7 cells. The greater expression of COX IV may allow 123.7 cells to maintain mitochondrial electron flow and energy production under drastically reduced oxygen conditions. Antioxidant treatment blocked hypoxia-induced cell death, but was not sufficient to prevent depletion of ATP or to modulate the metabolic pathways. Thus, this finding indicates that hypoxia-induced metabolic regulation and energy depletion occur independently of oxidative stress. Consequently, the PKA signaling pathway appears

Why?

$6

WHY? Why do African American children fill the rolls of low achievers? Why do African American children fill the rolls of needs improvement schools? Why do African American children fill the rolls of high school dropouts? Why do African American children fill the rolls of special education classes? The answers to these questions are not found in the traditional educational setting; nor are they found in the plethora of text devoted to social, economic, and educational reforms. The sub proficiency performances of many African American children in reading and reading comprehension contribute significantly to the educational, social, health and economic gaps in our schools and our society. As witnessed by many, it is the ability to read which allows a child to transcend even the poorest environment and social circumstances, and succeed in life. The ability to read is not innate; it is a learned skill that is dependent on the development of the neural (brain) cells necessary for memory. Sleep disordered breathing conditions, like Obstructive Sleep Apnea Syndrome (OSAS), impact the development of these cells and learning to read becomes difficult. The early diagnosis and treatment of OSAS will give these children an opportunity to learn to read, not be left behind, and develop to their maximum potential. IF YOUR CHILD SNORES, HE/SHE MAY HAVE OBSTRUCTIVE SLEEP APNEA SYNDROME. ASK YOUR DOCTOR TODAY.

Why?

$8.53

WHY?Why do African American children fill the rolls of low achievers? Why do African American children fill the rolls of needs improvement schools?Why do African American children fill the rolls of high school dropouts?Why do African American children fill the rolls of special education classes?The answers to these questions are not found in the traditional educational setting; nor are they found in the plethora of text devoted to social, economic, and educational reforms. The sub proficiency performances of many African American children in reading and reading comprehension contribute significantly to the educational, social, health and economic gaps in our schools and our society. As witnessed by many, it is the ability to read which allows a child to transcend even the poorest environment and social circumstances, and succeed in life. The ability to read is not innate; it is a learned skill that is dependent on the development of the neural (brain) cells necessary for memory. Sleep disordered breathing conditions, like Obstructive Sleep Apnea Syndrome (OSAS), impact the development of these cells and learning to read becomes difficult. The early diagnosis and treatment of OSAS will give these children an opportunity to learn to read, not be left behind, and develop to their maximum potential.IF YOUR CHILD SNORES, HE/SHE MAY HAVE OBSTRUCTIVE SLEEP APNEA SYNDROME.ASK YOUR DOCTOR TODAY.

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